The TBC1D10C antibody - N-terminal region from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Rat, Bovine, Canine, Guinea Pig, Horse, and Porcine antigen. The TBC1D10C antibody - N-terminal region has been validated for the following applications: Western Blot.
Description
This is a rabbit polyclonal antibody against TBC1D10C. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM]